Open AccessMechanisms of favorable effects of Rho kinase inhibition on myocardial remodeling and systolic function after experimental myocardial infarction in the rat
Author(s) -
Claudia Mera,
Iván Godoy,
Renato Ramírez,
Jackeline Moya,
María Paz Ocaranza,
Jorge Jalil
Publication year - 2015
Publication title -
therapeutic advances in cardiovascular disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 33
eISSN - 1753-9455
pISSN - 1753-9447
DOI - 10.1177/1753944715609516
Subject(s) - medicine , myocardial infarction , cardiology , ventricular remodeling , cardioprotection
The objective of this study was to determine the molecular mechanisms by which cardiac Rho-associated coiled-coil containing protein kinase (ROCK) activation after myocardial infarction (MI) does intervene in cardiac systolic function decline and remodeling.
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