Angiotensin II receptor blockade and skeletal muscle metabolism in overweight and obese adults with elevated blood pressure
Author(s) -
Nabil E. Boutagy,
Elaina L. Marinik,
Ryan P. McMillan,
Angela S. Anderson,
Madlyn I. Frisard,
Brenda M. Davy,
Jose M. Rivero,
Kevin P. Davy,
Matthew W. Hulver
Publication year - 2015
Publication title -
therapeutic advances in cardiovascular disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 33
eISSN - 1753-9455
pISSN - 1753-9447
DOI - 10.1177/1753944714566426
Subject(s) - olmesartan , endocrinology , medicine , skeletal muscle , beta oxidation , angiotensin ii , angiotensin receptor , blood pressure , metabolism
Whether angiotensin II receptor blockade improves skeletal muscle fatty acid oxidation in overweight and obese humans is unknown. The purpose of the study was to test the hypothesis that the angiotensin II receptor blocker, olmesartan, would increase fatty acid oxidation and the activity of enzymes associated with oxidative metabolism in skeletal muscle of overweight and obese humans.
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