Thiazolidinedione associated volume overload and pulmonary hypertension | Zendy

Jeffrey E. Michaelson | Zendy

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Thiazolidinedione associated volume overload and pulmonary hypertension

Author(s) -

Jeffrey E. Michaelson

Publication year - 2008

Publication title -

therapeutic advances in cardiovascular disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.164

H-Index - 33

eISSN - 1753-9455

pISSN - 1753-9447

DOI - 10.1177/1753944708093413

Subject(s) - medicine , thiazolidinedione , rosiglitazone , pulmonary hypertension , volume overload , diabetes mellitus , type 2 diabetes , cardiology , adverse effect , type 2 diabetes mellitus , heart failure , intensive care medicine , endocrinology

Thiazolidinediones are currently indicated for the treatment of Type 2 Diabetes. This class of drugs has been associated with several adverse reactions associated with volume overload. This report describes a case of a 65 year old African—American female with a history of hypertension and obesity, and taking rosiglitazone (Avandia) for her Type 2 Diabetes whose evaluation for chest pain resulted in the incidental finding of pulmonary hypertension noted on echocardiogram. The subsequent evaluation, follow-up and treatment are discussed along with potential pitfalls and implications for clinical care.

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