The impact of comorbidities on mortality among men and women with COPD: report from the OLIN COPD study | Zendy

Sawalha Sami | Zendy; Hedman Linnea | Zendy; Backman Helena | Zendy; Stenfors Nikolai | Zendy; Rönmark Eva | Zendy; Lundbäck Bo | Zendy; Lindberg Anne | Zendy

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The impact of comorbidities on mortality among men and women with COPD: report from the OLIN COPD study

Author(s) -

Sawalha Sami,

Hedman Linnea,

Backman Helena,

Stenfors Nikolai,

Rönmark Eva,

Lundbäck Bo,

Lindberg Anne

Publication year - 2019

Publication title -

therapeutic advances in respiratory disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.022

H-Index - 37

eISSN - 1753-4666

pISSN - 1753-4658

DOI - 10.1177/1753466619860058

Subject(s) - medicine , copd , diabetes mellitus , airway obstruction , population , depression (economics) , vital capacity , comorbidity , body mass index , mortality rate , obstructive lung disease , physical therapy , airway , lung , surgery , lung function , endocrinology , diffusing capacity , environmental health , economics , macroeconomics

Background: Comorbidities probably contribute to the increased mortality observed among subjects with chronic obstructive pulmonary disease (COPD), but sex differences in the prognostic impact of comorbidities have rarely been evaluated in population-based studies. The aim of this study was to evaluate the impact of common comorbidities, cardiovascular disease (CVD), diabetes mellitus (DM), and anxiety/depression (A/D), on mortality among men and women with and without airway obstruction in a population-based study.Methods: All subjects with airway obstruction [forced expiratory volume in 1 second (FEV 1 )/(forced) vital capacity ((F)VC) <0.70, n = 993] were, together with age- and sex-matched referents, identified after examinations of population-based cohorts in 2002–2004. Spirometric groups: normal lung function (NLF) and COPD (post-bronchodilator FEV 1 /(F)VC <0.70) and additionally, LLN-COPD (FEV 1 /(F)VC

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