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Real-world outcomes in patients with chronic obstructive pulmonary disease initiating long-acting mono bronchodilator therapy
Author(s) -
Lindsay G.S. Bengtson,
Michael DePietro,
Jeffrey McPheeters,
Kathleen M. Fox
Publication year - 2018
Publication title -
therapeutic advances in respiratory disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.022
H-Index - 37
eISSN - 1753-4666
pISSN - 1753-4658
DOI - 10.1177/1753466618772750
Subject(s) - medicine , bronchodilator , copd , discontinuation , bronchodilator agents , health care , intensive care medicine , physical therapy , emergency medicine , asthma , economics , economic growth
Patients initiating long-acting mono bronchodilator therapy had high rates of medication discontinuation or augmentation. Patients used more rescue medications and experienced significantly more COPD exacerbations with higher healthcare costs compared with baseline. Further research is warranted to determine whether more aggressive initial therapy would result in symptom improvement.

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