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Effect of 12 weeks of once-daily tiotropium/olodaterol on exercise endurance during constant work-rate cycling and endurance shuttle walking in chronic obstructive pulmonary disease
Author(s) -
François Maltais,
Denis E. O’Donnell,
Juan Bautista Gáldiz Iturri,
AnneMarie Kirsten,
Dave Singh,
Alan Hamilton,
Kay Tetzlaff,
Yihua Zhao,
Richard Casaburi
Publication year - 2018
Publication title -
therapeutic advances in respiratory disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.022
H-Index - 37
eISSN - 1753-4666
pISSN - 1753-4658
DOI - 10.1177/1753465818755091
Subject(s) - medicine , placebo , copd , clinical endpoint , anesthesia , physical therapy , randomized controlled trial , alternative medicine , pathology
Tiotropium/olodaterol 5/5 µg improved endurance time during cycle ergometry versus placebo, with a strong tendency to also improve walking endurance time. [ ClinicalTrials.gov identifier: NCT01525615.].

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