Open AccessAlbumin versus balanced crystalloid for resuscitation in the treatment of sepsis: A protocol for a randomised controlled feasibility study, “ABC-Sepsis”
Author(s) -
John Cafferkey,
Andrew Ferguson,
Julia Grahamslaw,
Katherine Oatey,
John Norrie,
Nazir Lone,
Timothy Walsh,
Daniel Horner,
Andy Appelboam,
Peter Hall,
Richard J.E. Skipworth,
Derek Bell,
Kevin Rooney,
Manu Shankar-Hari,
Alasdair Corfield,
Alasdair Gray
Publication year - 2022
Publication title -
the journal of the intensive care society/journal of the intensive care society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.551
H-Index - 14
eISSN - 2057-360X
pISSN - 1751-1437
DOI - 10.1177/17511437221103692
Subject(s) - medicine , resuscitation , sepsis , septic shock , protocol (science) , intensive care medicine , early warning score , randomized controlled trial , emergency department , emergency medicine , clinical trial , intensive care , severe sepsis , shock (circulatory) , surgery , nursing , alternative medicine , pathology
Patients presenting with suspected sepsis to secondary care often require fluid resuscitation to correct hypovolaemia and/or septic shock. Existing evidence signals, but does not demonstrate, a benefit for regimes including albumin over balanced crystalloid alone. However, interventions may be started too late, missing a critical resuscitation window.