Open AccessAlbumin versus balanced crystalloid for resuscitation in the treatment of sepsis: A protocol for a randomised controlled feasibility study, “ABC-Sepsis”
Author(s) -
John Cafferkey,
A Ferguson,
Julia Grahamslaw,
Katherine Oatey,
John Norrie,
Nazir Lone,
Timothy Walsh,
Daniel Horner,
Andy Appelboam,
Peter Hall,
Richard J.E. Skipworth,
Derek Bell,
Kevin Rooney,
Manu ShankarHari,
Alasdair Corfield,
Alasdair Gray
Publication year - 2022
Publication title -
journal of the intensive care society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.551
H-Index - 14
eISSN - 2057-360X
pISSN - 1751-1437
DOI - 10.1177/17511437221103692
Subject(s) - medicine , resuscitation , sepsis , septic shock , protocol (science) , intensive care medicine , early warning score , randomized controlled trial , emergency department , emergency medicine , clinical trial , intensive care , severe sepsis , shock (circulatory) , surgery , nursing , alternative medicine , pathology
Patients presenting with suspected sepsis to secondary care often require fluid resuscitation to correct hypovolaemia and/or septic shock. Existing evidence signals, but does not demonstrate, a benefit for regimes including albumin over balanced crystalloid alone. However, interventions may be started too late, missing a critical resuscitation window.
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