Exertional Heat Stroke – The Athlete's Nemesis

Heat stroke represents the extreme end of a spectrum of heat-related illnesses. It can occur in endurance athletes. Its incidence is probably under-reported. Patients present confused, drowsy or comatose, with a raised core temperature, but often a falsely reassuring peripheral temperature. Treatment is centred on reducing the core temperature as rapidly as possible and appropriate supportive management. Even with prompt treatment, it is associated with multi-organ dysfunction and death. Patients are often misdiagnosed, or diagnosed late. This is probably exacerbated by a wide differential diagnosis, the need for a core temperature measurement to reach the diagnosis and clinicians being unfamiliar with the disease. The need for immediate recognition, and immediate treatment compounds the problem. Survivors may experience long-term neurological disability and may be at risk of a further episode. Patients should return to sport gradually and only when they feel well. Its epidemiology, pathophysiology and clinical management are reviewed.