Overdose of Ferrous Sulphate, Co-Dydramol and Non-Steroidal Anti-Inflammatory Drugs, Leading to Fatal Hepatotoxicity | Zendy

Namita Sharma | Zendy; Alison Hall | Zendy; Ann Holden | Zendy

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Overdose of Ferrous Sulphate, Co-Dydramol and Non-Steroidal Anti-Inflammatory Drugs, Leading to Fatal Hepatotoxicity

Author(s) -

Namita Sharma,

Alison Hall,

Ann Holden

Publication year - 2011

Publication title -

journal of the intensive care society

Language(s) - English

Resource type - Journals

eISSN - 2057-360X

pISSN - 1751-1437

DOI - 10.1177/175114371101200311

Subject(s) - ferrous sulphate , ferrous , medicine , polypharmacy , toxicity , shock (circulatory) , pharmacology , chemistry , inorganic chemistry , organic chemistry

A 27-year-old woman died within 48 hours of an overdose of ferrous sulphate, co-dydramol and non-steroidal anti-inflammatory drugs (NSAIDs) from shock secondary to acute liver failure. Her serum iron level at five hours postingestion was lower than that of many non-fatal, pure ferrous sulphate overdoses in published studies. This case highlights the importance of knowing the signs, symptoms and prognostication of ferrous sulphate toxicity and appreciation of the cumulative fatal effects of polypharmacy overdose.

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