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An ‘open-lung’ ventilation strategy that includes low tidal volumes, recruitment manoeuvres and high levels of PEEP does not reduce hospital mortality in patients with acute lung injury or acute respiratory distress syndrome    Level of evidence: 1 +  (RCT with a low risk of bias)

‘Open-lung’ Ventilation Strategies and Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS)