Role of fragile X mental retardation protein in chronic pain | Zendy

Xiangyang Mei | Zendy; Yixin Yang | Zendy; Jinsong Zhao | Zendy; Yongjie Wang | Zendy; QiLiang Chen | Zendy; Xiang Qian | Zendy; XiangYao Li | Zendy; Zhiying Feng | Zendy

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Role of fragile X mental retardation protein in chronic pain

Author(s) -

Xiangyang Mei,

Yixin Yang,

Jinsong Zhao,

Yongjie Wang,

QiLiang Chen,

Xiang Qian,

XiangYao Li,

Zhiying Feng

Publication year - 2020

Publication title -

molecular pain

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.081

H-Index - 83

ISSN - 1744-8069

DOI - 10.1177/1744806920928619

Subject(s) - fragile x , chronic pain , fragile x syndrome , sensitization , neuroscience , medicine , psychology , psychiatry , biology , genetics , gene

Chronic pain has detrimental effects on one’s quality of life. However, its treatment options are very limited, and its underlying pathogenesis remains unclear. Recent research has suggested that fragile X mental retardation protein is involved in the development of chronic pain, making it a potential target for prevention and treatment. The current review of literature will examine the function of fragile X mental retardation protein and its associated pathways, through which we hope to gain insight into how fragile X mental retardation protein may contribute to nociceptive sensitization and chronic pain.

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