Precision prevention: A focused response to shifting paradigms in healthcare | Zendy

Kenneth S. Ramos | Zendy; Emma C. Bowers | Zendy; Marco A. Tavera-Garcia | Zendy; Irma N. Ramos | Zendy

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Precision prevention: A focused response to shifting paradigms in healthcare

Author(s) -

Kenneth S. Ramos,

Emma C. Bowers,

Marco A. Tavera-Garcia,

Irma N. Ramos

Publication year - 2019

Publication title -

experimental biology and medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.012

H-Index - 146

eISSN - 1535-3702

pISSN - 1535-3699

DOI - 10.1177/1535370219829759

Subject(s) - pulmonary disease , medicine , disease , pathogenesis , intensive care medicine , spare part , copd , health care , lung cancer , precision medicine , lung disease , lung , bioinformatics , risk analysis (engineering) , immunology , pathology , biology , operations management , engineering , economics , economic growth

The study of LINE-1 retroelements and their role in the pathogenesis of diseases of the lung such as COPD and lung cancer may provide valuable diagnostic and therapeutic tools to identify pre-emptively individuals at risk of pulmonary disease progression. Limited information is presently available on the role of LINE-1 in the regulation of disease phenotypes and the development of novel therapeutics designed to curtail LINE-1-mediated pathogenesis. Successful implementation of precision prevention strategies may help to spare those impacted by obstructive pulmonary disease from continued deterioration, while realizing significant cost savings and improved quality of healthcare.

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