Uric Acid and the Risk of Alzheimer’s Disease | Zendy

Min Yuan | Zendy; Lijun Xu | Zendy; Xiaoping Yin | Zendy

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Uric Acid and the Risk of Alzheimer’s Disease

Author(s) -

Min Yuan,

Lijun Xu,

Xiaoping Yin

Publication year - 2015

Publication title -

american journal of alzheimer s disease and other dementias®

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.653

H-Index - 60

eISSN - 1938-2731

pISSN - 1533-3175

DOI - 10.1177/1533317515602550

Subject(s) - uric acid , dementia , disease , prospective cohort study , alzheimer's disease , medicine , prospective memory , association (psychology) , cognition , cognitive impairment , gerontology , neuroscience , psychology , psychiatry , psychotherapist

Alzheimer's disease (AD) is a very common neurodegenerative disorder of the central nervous system, characterized by dementia, cognitive impairment, and memory loss, and the global prevalence is increasing. Many epidemiologic studies have considered the association between uric acid and AD, yet the relationship remains elusive. The objective of this study was to validate whether or not uric acid is indeed associated with AD. We compared different prospective studies and ultimately found that it is also a controversial issue. Further higher quality prospective evidence on the relationship between uric acid and AD in different age stage are needed to determine the causal association and its exact pathogenetic mechanisms.

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