Optimization of Single Voxel MR Spectroscopy Sequence Parameters and Data Analysis Methods for Thermometry in Deep Hyperthermia Treatments
Author(s) -
Josefin Hartmann,
Johanna Gellermann,
Tobias Brandt,
Manfred Schmidt,
Stanislav Pyatykh,
Jürgen Hesser,
Oliver J. Ott,
Rainer Fietkau,
Christoph Bert
Publication year - 2016
Publication title -
technology in cancer research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 63
eISSN - 1533-0346
pISSN - 1533-0338
DOI - 10.1177/1533034616656310
Subject(s) - flip angle , voxel , imaging phantom , nuclear magnetic resonance , spectroscopy , magnetic resonance imaging , calibration , pulse sequence , singular value decomposition , nuclear magnetic resonance spectroscopy , chemistry , optics , materials science , computational physics , physics , mathematics , algorithm , computer science , statistics , medicine , quantum mechanics , artificial intelligence , radiology
The difference in the resonance frequency of water and methylene moieties of lipids quantifies in magnetic resonance spectroscopy the absolute temperature using a predefined calibration curve. The purpose of this study was the investigation of peak evaluation methods and the magnetic resonance spectroscopy sequence (point-resolved spectroscopy) parameter optimization that enables thermometry during deep hyperthermia treatments.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom