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Optimization of Single Voxel MR Spectroscopy Sequence Parameters and Data Analysis Methods for Thermometry in Deep Hyperthermia Treatments
Author(s) -
Josefin Hartmann,
Johanna Gellermann,
Tobias Brandt,
Manfred Schmidt,
Stanislav Pyatykh,
Jürgen Hesser,
Oliver J. Ott,
Rainer Fietkau,
Christoph Bert
Publication year - 2016
Publication title -
technology in cancer research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 63
eISSN - 1533-0346
pISSN - 1533-0338
DOI - 10.1177/1533034616656310
Subject(s) - flip angle , voxel , imaging phantom , nuclear magnetic resonance , spectroscopy , magnetic resonance imaging , calibration , pulse sequence , singular value decomposition , nuclear magnetic resonance spectroscopy , chemistry , optics , materials science , computational physics , physics , mathematics , algorithm , computer science , statistics , medicine , quantum mechanics , artificial intelligence , radiology
The difference in the resonance frequency of water and methylene moieties of lipids quantifies in magnetic resonance spectroscopy the absolute temperature using a predefined calibration curve. The purpose of this study was the investigation of peak evaluation methods and the magnetic resonance spectroscopy sequence (point-resolved spectroscopy) parameter optimization that enables thermometry during deep hyperthermia treatments.

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