Association of Mixed Lineage Kinase Domain-Like Protein Expression With Prognosis in Patients With Colon Cancer
Author(s) -
Xian Li,
Jing Guo,
Aiping Ding,
Weiwei Qi,
Peihua Zhang,
Jing Lv,
Wensheng Qiu,
Zhenqing Sun
Publication year - 2016
Publication title -
technology in cancer research and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 63
eISSN - 1533-0346
pISSN - 1533-0338
DOI - 10.1177/1533034616655909
Subject(s) - medicine , colorectal cancer , proportional hazards model , oncology , protein kinase a , survival analysis , cancer , immunohistochemistry , kinase , cancer research , biology , microbiology and biotechnology
The mixed lineage kinase domain-like protein has recently been identified as a key downstream component of tumor necrosis factor-induced necroptosis, which is an important pathway of cancer cell death. The goal of the current study is to explore the expression of mixed lineage kinase domain-like protein in colon cancer tissues and evaluate the prognostic value in patients with colon cancer.
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