Long-term effects of adrenalectomy or spironolactone on blood pressure control and regression of left ventricle hypertrophy in patients with primary aldosteronism | Zendy

Tomáš Indra | Zendy; Robert Holaj | Zendy; Branislav Štrauch | Zendy; J. Rosa | Zendy; Ondřej Petrák | Zendy; Zuzana Šomlóová | Zendy; J Widimský | Zendy

Open Access

Long-term effects of adrenalectomy or spironolactone on blood pressure control and regression of left ventricle hypertrophy in patients with primary aldosteronism

Author(s) -

Tomáš Indra,

Robert Holaj,

Branislav Štrauch,

J. Rosa,

Ondřej Petrák,

Zuzana Šomlóová,

J Widimský

Publication year - 2014

Publication title -

journal of the renin-angiotensin-aldosterone system

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 46

eISSN - 1752-8976

pISSN - 1470-3203

DOI - 10.1177/1470320314549220

Subject(s) - primary aldosteronism , spironolactone , medicine , interventricular septum , cardiology , adrenalectomy , blood pressure , ventricle , aldosterone , left ventricular hypertrophy , muscle hypertrophy , diastole , heart failure , endocrinology

Primary aldosteronism (PA) represents the most common cause of secondary hypertension. Beyond increased blood pressure, additional harmful effects of aldosterone excess including inappropriate left ventricle (LV) hypertrophy were found. We evaluated the effect of adrenalectomy and spironolactone on blood pressure and myocardial remodelling in a long-term follow-up study.

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