Novel findings: Expression of angiotensin-converting enzyme and angiotensin-converting enzyme 2 in thoracic aortic dissection and aneurysm
Author(s) -
Yang Li,
Jia Hu,
Hong Qian,
Jun Gu,
Wei Meng,
Eryong Zhang
Publication year - 2014
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320314549219
Subject(s) - aortic dissection , aneurysm , medicine , dissection (medical) , aortic aneurysm , thoracic aortic aneurysm , angiotensin converting enzyme 2 , cardiology , renin–angiotensin system , angiotensin converting enzyme , angiotensin ii , thoracic aorta , aorta , coronary artery disease , surgery , disease , blood pressure , covid-19 , infectious disease (medical specialty)
Angiotensin-converting enzyme (ACE) and ACE2 are key regulators of the renin-angiotensin system, which has been shown to participate in a series of cardiovascular diseases. We hypothesized that dysregulated gene expression of ACE and ACE2 contribute to the formation of thoracic aortic dissection and aneurysm.
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