Open AccessRelationship between polymorphism of angiotensin-converting enzyme gene insertion/deletion and risk of hepatocellular carcinoma in a Chinese Dai population
Author(s) -
Yong Zha,
Ping Gan,
Qin Liu,
Jing Tan
Publication year - 2014
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320314539829
Subject(s) - hepatocellular carcinoma , chinese population , gene , genetics , angiotensin converting enzyme , polymorphism (computer science) , biology , population , oncology , angiotensin ii , medicine , cancer research , allele , genotype , environmental health , blood pressure , receptor
The angiotensin-converting enzyme gene (ACE) is directly involved in the process of cancer cell proliferation, differentiation, apoptosis and angiogenesis. It also plays a vital role in inducing liver fibrosis and developing hepatocellular carcinoma (HCC). The aim of this study was to investigate the relationship between ACE insertion/deletion (I/D) polymorphism and the risk of HCC in a Chinese Dai population.
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