Open AccessFetal kidney programming by severe food restriction: Effects on structure, hormonal receptor expression and urinary sodium excretion in rats
Author(s) -
Bárbara Vaccari Cardoso,
Flávia Fernandes Mesquita,
José Antônio Rocha Gontijo,
Patrícia Aline Boer
Publication year - 2013
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320313481081
Subject(s) - endocrinology , medicine , offspring , nephron , mineralocorticoid receptor , kidney , renal function , mineralocorticoid , angiotensin ii , urinary system , aldosterone , excretion , biology , blood pressure , pregnancy , genetics
The present study investigates, in 23-day-old and adult male rats, the effect of severe food restriction in utero on blood pressure (BP), and its association with nephron structure and function changes, angiotensin II (AT1R/AT2R), glucocorticoid (GR) and mineralocorticoid (MR) receptor expression.
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