Open AccessAssociation of polymorphisms in the AGT gene with essential hypertension in the Chinese population
Author(s) -
Bo Xi,
Yue Shen,
Yinkun Yan,
Jie Mi
Publication year - 2011
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320311430991
Subject(s) - odds ratio , meta analysis , confidence interval , essential hypertension , polymorphism (computer science) , medicine , genetic model , chinese population , genetics , pathogenesis , population , gene polymorphism , bioinformatics , genotype , biology , gastroenterology , gene , blood pressure , environmental health
Although the angiotensinogen (AGT) gene has been implicated in the pathogenesis of essential hypertension, the results have been inconsistent. In this study, we performed a meta-analysis to assess the association of A-6G, A-20C and G-217A polymorphisms in the AGT gene with essential hypertension in the Chinese population.