Open AccessAssociation of angiotensin-converting enzyme gene insertion/deletion polymorphism with high-altitude pulmonary oedema: a meta-analysis
Author(s) -
Yue Qi,
Jiayi Sun,
Tongchun Zhu,
Wei Wang,
Jing Liu,
Wu-qing Zhou,
Changchun Qiu,
Dong Zhao
Publication year - 2011
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320311406572
Subject(s) - odds ratio , meta analysis , medicine , genotype , confidence interval , allele , publication bias , angiotensin converting enzyme , cochrane library , genetics , biology , gene , blood pressure
High-altitude pulmonary oedema (HAPE) is a non-cardiogenic hydrostatic oedema involving a genetic component. Considering the low incidence of HAPE, sample sizes in current reports are relatively limited. We aimed to assess the association between the angiotensin-converting enzyme (ACE) I/D polymorphism and HAPE via a meta-analysis of published and unpublished data.