Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects | Zendy

Vasudevan Ramachandran | Zendy; Patimah Ismail | Zendy; Johnson Stanslas | Zendy; Norashikin Shamsudin | Zendy; Saidi Moin | Zendy; Rusni Mohd Jas | Zendy

Open Access

Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects

Author(s) -

Vasudevan Ramachandran,

Patimah Ismail,

Johnson Stanslas,

Norashikin Shamsudin,

Saidi Moin,

Rusni Mohd Jas

Publication year - 2008

Publication title -

journal of the renin-angiotensin-aldosterone system

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 46

eISSN - 1752-8976

pISSN - 1470-3203

DOI - 10.1177/1470320308097499

Subject(s) - genotype , angiotensin converting enzyme , genotyping , allele , medicine , type 2 diabetes mellitus , allele frequency , polymorphism (computer science) , endocrinology , essential hypertension , diabetes mellitus , gene polymorphism , gene , genetics , biology , blood pressure

The deletion (D) allele of the angiotensin-converting enzyme (ACE) gene has been studied in various populations in relation to hypertension (HTN) and type 2 diabetes mellitus (T2DM) with contradictory results. This study sought to determine the association of insertion (I)/D polymorphism of the ACE gene in hypertensive and T2DM subjects in a Malaysian population.

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