HISTOCHEMICAL DEMONSTRATION OF NOREPINEPHRINE AT A FINE STRUCTURAL LEVEL
Author(s) -
Joe Wood,
Russell J. Barrnett
Publication year - 1964
Publication title -
journal of histochemistry and cytochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 124
eISSN - 1551-5044
pISSN - 0022-1554
DOI - 10.1177/12.3.197
Subject(s) - epinephrine , norepinephrine , adrenal medulla , catecholamine , endocrinology , medicine , chemistry , biology , dopamine
The present work describes a method for the histochemical demonstration of, and the differentiation between, norepinephrine and epinephrine at a fine structural level in cells of the adrenal medulla. The two catecholamines are definitely contained in granules which occur in two different cell types; one for norepinephrine, the other for epinephrine. No evidence could be adduced from the present material that norepinephrine material served as a precursor for epinephrine granules. Preliminary observations are included on the occurence of catecholamine-containing granules in neuronal processes of the hypothalamus.
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