Open AccessAdenosquamous Carcinoma of the Pancreas
Author(s) -
Del Arco Hélène,
Chakiba-Brugère Camille,
Salabert Laura,
Béchade Dominique
Publication year - 2019
Publication title -
clinical medicine insights: oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 26
ISSN - 1179-5549
DOI - 10.1177/1179554919886587
Subject(s) - adenosquamous carcinoma , medicine , pancreas , chemotherapy , radiology , carcinoma , folfiri , abdominal pain , oncology , general surgery , adenocarcinoma , oxaliplatin , cancer , colorectal cancer
A 60-year-old woman presented to hospital with abdominal pain and massive weight loss. Imaging studies confirmed the presence of a tumor of the pancreas. Histologic analysis of the sampling performed by echoendoscopic ultrasound fine-needle aspiration found aspects evocative of adenosquamous carcinoma. This case report highlights the difficulties of clinical pathologic diagnosis for these occasionally composite tumors. The patient underwent palliative chemotherapy based on platinum and 5-fluorouracil, followed by second-line chemotherapy with FOLFIRI after progression. Adenosquamous carcinoma of the pancreas remains a rare tumor with very poor prognosis and limited therapeutic options.
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