Open AccessA Clinical Update on Vasoactive Medication in the Management of Cardiogenic Shock
Author(s) -
Aditi Shankar,
Gayathri Gurumurthy,
Lakshmi Sridharan,
Divya Gupta,
William Nicholson,
Wissam Jaber,
Saraschandra Vallabhajosyula
Publication year - 2022
Publication title -
clinical medicine insights. cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 21
ISSN - 1179-5468
DOI - 10.1177/11795468221075064
Subject(s) - cardiogenic shock , inotrope , vasoactive , septic shock , medicine , shock (circulatory) , intensive care medicine , mechanism (biology) , cardiology , sepsis , myocardial infarction , philosophy , epistemology
This is a focused review looking at the pharmacological support in cardiogenic shock. There are a plethora of data evaluating vasopressors and inotropes in septic shock, but the data are limited for cardiogenic shock. This review article describes in detail the pathophysiology of cardiogenic shock, the mechanism of action of different vasopressors and inotropes emphasizing their indications and potential side effects. This review article incorporates the currently used specific risk-prediction models in cardiogenic shock as well as integrates data from many trials on the use of vasopressors and inotropes. Lastly, this review seeks to discuss the future direction for vasoactive medications in cardiogenic shock.