Citrulline Improves Early Post-Ischemic Recovery or Rat Hearts In Vitro by Shifting Arginine Metabolism From Polyamine to Nitric Oxide Formation
Author(s) -
Marc Heidorn,
Tim Frodermann,
Andreas Böning,
Rolf Schreckenberg,
KlausDieter Schlüter
Publication year - 2018
Publication title -
clinical medicine insights cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 21
ISSN - 1179-5468
DOI - 10.1177/1179546818771908
Subject(s) - citrulline , nitric oxide , arginine , inotrope , arginase , ischemia , medicine , nitric oxide synthase , chemistry , reperfusion therapy , endocrinology , polyamine , perfusion , pharmacology , biochemistry , amino acid
Citrulline, known to block arginase and to support NO formation, improves the early functional recovery of post-ischemic hearts and may be an alternative to catecholamines to improve early post-ischemic recovery.
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