Open AccessExamining the Relationship Between Gastroschisis and Placental Fetal Vascular Malperfusion
Author(s) -
Brittany Ann Ruschkowski,
Ahmed Nasr,
Irina Oltean,
Sarah Lawrence,
Dina El Demellawy
Publication year - 2021
Publication title -
pediatric and developmental pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.477
H-Index - 60
eISSN - 1615-5742
pISSN - 1093-5266
DOI - 10.1177/10935266211029629
Subject(s) - gastroschisis , medicine , omphalocele , abdominal wall , fetus , pregnancy , abdominal wall defect , obstetrics , maldevelopment , placenta , pathogenesis , intestinal atresia , pathology , surgery , anatomy , biology , atresia , genetics
Gastroschisis is a congenital malformation characterized by intestinal herniation through an abdominal wall defect. Despite its unknown pathogenesis, known risk factors include maternal smoking, alcohol use, and young maternal age. Previous work has shown that gastroschisis is associated with placental delayed villous maturation, and the goal of this study was to assess for additional associated placental pathologies that may help clarify the pathogenesis of gastroschisis.