Safety Assessment of Alkyl Phosphates as Used in Cosmetics | Zendy

Fiume Monice M. | Zendy; Bergfeld Wilma F. | Zendy; Belsito Donald V. | Zendy; Hill Ronald A. | Zendy; Klaassen Curtis D. | Zendy; Liebler Daniel C. | Zendy; Marks James G. | Zendy; Shank Ronald C. | Zendy; Slaga Thomas J. | Zendy; Snyder Paul W. | Zendy; Gill Lillian J. | Zendy; Heldreth Bart | Zendy

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Safety Assessment of Alkyl Phosphates as Used in Cosmetics

Author(s) -

Fiume Monice M.,

Bergfeld Wilma F.,

Belsito Donald V.,

Hill Ronald A.,

Klaassen Curtis D.,

Liebler Daniel C.,

Marks James G.,

Shank Ronald C.,

Slaga Thomas J.,

Snyder Paul W.,

Gill Lillian J.,

Heldreth Bart

Publication year - 2019

Publication title -

international journal of toxicology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.432

H-Index - 58

eISSN - 1092-874X

pISSN - 1091-5818

DOI - 10.1177/1091581819856582

Subject(s) - alkyl , cosmetics , phosphate , chemistry , plasticizer , toxicology , organic chemistry , biology

The Expert Panel assessed the safety of 28 alkyl phosphates and concluded that these ingredients are safe in the current practices of use and concentration when formulated to be nonirritating. The ingredients in the alkyl phosphate family share a common phosphate core structure, and vary by the identity of the alkyl chains attached therein. Most of the alkyl phosphates function as surfactants in cosmetic ingredients; however, the triesters function as plasticizers rather than surfactants. The Panel reviewed the available animal and clinical data to determine the safety of these ingredients.

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