Decision Algorithms for Direct Oral Anticoagulant Use in Patients With Nonvalvular Atrial Fibrillation: A Practical Guide for Neurologists | Zendy

Isabella Canavero | Zendy; Giuseppe Micieli | Zendy; Maurizio Paciaroni | Zendy

Open Access

Decision Algorithms for Direct Oral Anticoagulant Use in Patients With Nonvalvular Atrial Fibrillation: A Practical Guide for Neurologists

Author(s) -

Isabella Canavero,

Giuseppe Micieli,

Maurizio Paciaroni

Publication year - 2017

Publication title -

clinical and applied thrombosis/hemostasis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 53

eISSN - 1938-2723

pISSN - 1076-0296

DOI - 10.1177/1076029617720068

Subject(s) - atrial fibrillation , medicine , vitamin k , intensive care medicine , anticoagulant therapy , stroke (engine) , oral anticoagulant , warfarin , cardiology , mechanical engineering , engineering

Direct oral anticoagulants (DOACs) are valid alternative options to vitamin K antagonists due to their limited interactions with drugs or food and the fact that they do not require regular coagulation monitoring. To this regard, recent practice guidelines recommend that DOACs should be considered as first-line anticoagulant therapy for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF). This review (1) outlines current international guidelines for the management of DOACs to prevent stroke in patients with NVAF, (2) outlines indications for elderly patients as well as specific settings including acute coronary syndromes and intracranial hemorrhage, and (3) offers a practical guide for the use of DOACs in neurological settings.

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