Tricyclic Antidepressants Modulate Stressed Mitochondria in Glioblastoma Multiforme Cells | Zendy

Anna Bielecka | Zendy; Tomasz Ludyga | Zendy; Grzegorz Machnik | Zendy; Miłosz Gołyszny | Zendy; Ewa Obuchowicz | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Tricyclic Antidepressants Modulate Stressed Mitochondria in Glioblastoma Multiforme Cells

Author(s) -

Anna Bielecka,

Tomasz Ludyga,

Grzegorz Machnik,

Miłosz Gołyszny,

Ewa Obuchowicz

Publication year - 2018

Publication title -

cancer control

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.794

H-Index - 72

eISSN - 1526-2359

pISSN - 1073-2748

DOI - 10.1177/1073274818798594

Subject(s) - mitochondrion , imipramine , medicine , tricyclic , reactive oxygen species , amitriptyline , pharmacology , tricyclic antidepressant , cancer research , antidepressant , pathology , microbiology and biotechnology , biology , hippocampus , alternative medicine

In the light of reported studies, the mitochondrial disturbance observed in glioma cells is a dynamic process that can be reversed or silenced. Moreover, imipramine and amitriptyline are attractive cellular metabolic modulators and can potentially be used to restoring a proper function of mitochondria in GBM cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research