Chordoma of the sacrum of an adult naked mole-rat
Author(s) -
Cole Jordan E.,
Steeil James C.,
Sarro Steven J.,
Kerns Kenton L.,
Cartoceti Andrew
Publication year - 2020
Publication title -
journal of veterinary diagnostic investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.529
H-Index - 78
eISSN - 1943-4936
pISSN - 1040-6387
DOI - 10.1177/1040638719894985
Subject(s) - sacrum , chordoma , anatomy , biology , medicine , pathology
The naked mole-rat (NMR; Heterocephalus glaber )—a small, eusocial, subterranean rodent native to East Africa—is distinguished by its capability to live long and resist changes associated with the aging process. Notably, a growing amount of research has been dedicated to NMRs’ multifactorial capacity to resist cancer. Since 2016, however, zoos have begun to document various neoplasms in a handful of individuals. We present herein radiographic, gross anatomic, and histopathologic features of a case of a sacral chordoma in a geriatric female. Chordomas originate in notochordal remnants. These spinal tumors are most commonly seen in ferrets; chordomas are rare in humans, can be difficult to treat, and need wide surgical margins.
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