Open AccessInfantil delirium induced by cycloplegic eye drops
Author(s) -
Turan Caner,
Keskin Gulsum,
Gunes Sebla,
Yurtseven Ali,
Saz Eylem Ulas
Publication year - 2018
Publication title -
hong kong journal of emergency medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 12
eISSN - 2309-5407
pISSN - 1024-9079
DOI - 10.1177/1024907917748726
Subject(s) - medicine , tropicamide , cyclopentolate , anesthesia , cycloplegia , mydriasis , atropine , fundus (uterus) , delirium , papilledema , anticholinergic , eye examination , coma (optics) , ophthalmology , pediatrics , pupil , eye disease , intensive care medicine , visual acuity , refractive error , physics , optics , neuroscience , biology
Cyclopentolate 1% and tropicamide 1% eye drops are considered to be safe in the pediatric population for the fundus examination and treatment of ocular diseases. Although adverse reactions rarely occur, some of them can be life‐threatening such as seizure, delirium, coma, arrhythmia, acute life‐threatening event, and death. Here we report 15 months old boy who developed delirium after administration of ocular cyclopentolate 1% drops in both eyes during a routine examination for retinopathy of prematurity. Cyclopentolate is a parasympatholytic drug with actions similar to atropine. With ophthalmic administration of cyclopentolate, severe central nervous system effects and systemic reactions may occur. In order to minimize absorption following instill one or two drops of 1% solution, applying pressure to nasolacrimal sac for 2 to 3 min should be considered. In mild to moderate toxicity, benzodiazepines may be used to control central nervous system findings secondary to anticholinergic effects.