Open AccessProlonged Qt Interval after Fexofenadine Overdose in the Presence of Hypokalemia and Hypocalcaemia
Author(s) -
Aksakal E,
Ulus T,
Taş H,
Ocak T,
Sevimli S
Publication year - 2010
Publication title -
hong kong journal of emergency medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 12
eISSN - 2309-5407
pISSN - 1024-9079
DOI - 10.1177/102490791001700114
Subject(s) - medicine , hypokalemia , qt interval , anesthesia , bradycardia , hypocalcaemia , gastric lavage , emergency department , heart rate , blood pressure , calcium , psychiatry
A 23‐year‐old healthy woman was admitted to our emergency department because of syncope and unconsciousness. She had taken 20 tablets of fexofenadine (total 2400 mg) and 9 tablets of furosemide (total 360 mg) for suicide. The electrocardiogram demonstrated bradycardia (48/min) and markedly prolonged QTc interval (684 msec). Endotracheal intubation and nasogastric tube insertion were performed. Gastric lavage was implemented and activated charcoal was given. A transient pacemaker was implanted. Hypokalemia and hypocalcaemia were also present and the electrolyte disturbances were corrected. The heart rate and QTc interval returned to normal limits after treatment. She stayed in our hospital for seven days. She recovered completely and ventricular arrhythmia was not seen during the hospitalization period.