Open AccessImpact of 6-Month Aerobic Exercise on Alzheimer’s Symptoms
Author(s) -
Fang Yu,
William Thomas,
Nathaniel W. Nelson,
Ulf G. Bronas,
Maurice W. Dysken,
Jean F. Wyman
Publication year - 2013
Publication title -
journal of applied gerontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.857
H-Index - 50
eISSN - 1552-4523
pISSN - 0733-4648
DOI - 10.1177/0733464813512895
Subject(s) - aerobic exercise , gerontology , medicine , alzheimer's disease , physical therapy , psychology , physical medicine and rehabilitation , disease
Little is known about how aerobic exercise affects Alzheimer's disease (AD). The purpose of this pilot study was to test the impact of 6-month cycling on AD symptoms in community-dwelling older adults with mild-to-moderate AD, using a single-group, repeated-measures design (n = 26). AD symptoms were measured with the AD Assessment Scale-Cognitive (ADAS-Cog), Disability in AD (DAD), and Neuropsychiatric Inventory-Caregiver (NPI-Q) scales at baseline, 3 and 6 months. Data were analyzed using mixed linear models. The ADAS-Cog, DAD, and NPI-Q severity scores remained unchanged over the 6-month period, while caregiver distress decreased 40% (p < .05). We conclude that aerobic exercise may reduce AD symptoms and appears effective in decreasing caregiver distress. Further randomized controlled trials are needed to examine the effects of aerobic exercise in AD.
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