Open AccessBrain Aging and Alzheimer's Disease*
Author(s) -
Crapper Dr,
U. DeBoni
Publication year - 1978
Publication title -
canadian psychiatric association journal
Language(s) - English
Resource type - Journals
ISSN - 0008-4824
DOI - 10.1177/070674377802300406
Subject(s) - dementia , disease , pathological , alzheimer's disease , senile plaques , medicine , neuropathology , senile dementia , neuroscience , psychology , pathology
The most common cause of senile dementia appears to be a pathological process indistinguishable from that found in presenile dementia of the Alzheimer type. Consideration of the neuropathological changes suggest that this disease may involve the interaction of at least three processes: a viral-like infection, a disorder in the immune system and the neurotoxic effect of an environmental agent. The evidence in support of this hypothesis is reviewed.