Adipose-Derived Stem Cells Improve Collagenase-Induced Tendinopathy in a Rat Model | Zendy

Takashi Oshita | Zendy; Morikuni Tobita | Zendy; Satoshi Tajima | Zendy; Hiroshi Mizuno | Zendy

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Adipose-Derived Stem Cells Improve Collagenase-Induced Tendinopathy in a Rat Model

Author(s) -

Takashi Oshita,

Morikuni Tobita,

Satoshi Tajima,

Hiroshi Mizuno

Publication year - 2016

Publication title -

the american journal of sports medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.021

H-Index - 221

eISSN - 1552-3365

pISSN - 0363-5465

DOI - 10.1177/0363546516640750

Subject(s) - tendinopathy , medicine , tendon , collagenase , adipose tissue , saline , stem cell , type i collagen , pathology , transplantation , urology , chemistry , biology , enzyme , biochemistry , genetics

Tendinopathy is a common and highly prevalent musculoskeletal disorder characterized by repetitive activity-related pain and focal tendon tenderness. Histopathologically, tendinopathic tissue mainly shows degenerative changes. Therefore, tendinopathy is not affected by anti-inflammatory therapies. A novel approach, including a stem cell-based therapy, may be beneficial for its treatment.

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