Methohexitone-Induced Convulsions in Epileptics | Zendy

CHRISTOPHER G. MALE | Zendy; E.M. Allen | Zendy

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Methohexitone-Induced Convulsions in Epileptics

Author(s) -

CHRISTOPHER G. MALE,

E.M. Allen

Publication year - 1977

Publication title -

anaesthesia and intensive care

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 0.494

H-Index - 62

eISSN - 1448-0271

pISSN - 0310-057X

DOI - 10.1177/0310057x7700500307

Subject(s) - medicine , convulsion , status epilepticus , anesthesia , anticonvulsant , petit mal , grand mal , methohexital , epilepsy , myoclonic jerk , myoclonus , psychiatry , propofol

The risk of precipitating a convulsion in epileptic patients with methohexitone has been judged to vary widely. This article reports such complications arising during methohexitone-activated E.E.G. recording in a series of 48 epileptic patients from whom anticonvulsant medication was withheld. Two patients developed grand mal convulsions during induction with methohexitone 1-0%. Two others exhibited status epilepticus of the petit mal type and one of the myoclonic type, after stopping an infusion of 0-09% methohexitone. The specificity for methohexitone-induced convulsions in epileptics or crypto-epileptics is supported by a review of the literature.

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