Open AccessEffect of Buprenorphine on the Ventilatory Response to Carbon Dioxide
Author(s) -
T. J. Baster,
J. M. Gibbs,
Tra-My Justine Richardson
Publication year - 1977
Publication title -
anaesthesia and intensive care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 62
eISSN - 1448-0271
pISSN - 0310-057X
DOI - 10.1177/0310057x7700500205
Subject(s) - buprenorphine , medicine , anesthesia , analgesic , opioid , antagonist , carbon dioxide , receptor , ecology , biology
Buprenorphine is a potent synthetic opioid-partial antagonist analgesic drug currently under clinical trial. When administered intravenously to human volunteers buprenorphine produced a significant depression of the ventilatory response to carbon dioxide stimulus for a period in excess of six hours.
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