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Central Diabetes Insipidus: A Rare Perioperative Cause of Severe Hypernatraemia
Author(s) -
Awori J. Hayanga,
Robert B. Kohen,
Byron Egeland,
Anthony Charles,
Martinus T. Spoor,
W. M. Kuzon,
Lena M. Napolitano
Publication year - 2008
Publication title -
anaesthesia and intensive care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 62
eISSN - 1448-0271
pISSN - 0310-057X
DOI - 10.1177/0310057x0803600215
Subject(s) - medicine , desmopressin , diabetes insipidus , hypernatremia , perioperative , pediatrics , surgery , nephrogenic diabetes insipidus , diabetes mellitus , past medical history , primum non nocere , intensive care medicine , endocrinology , chemistry , organic chemistry , sodium
In this case report we describe the management of severe hypernatraemia following inadvertent water restriction. A 21-year-old woman with no reported medical history presented on transfer from an outside hospital with a complex volar upper extremity injury. Management both operatively and postoperatively involved a prolonged period of fasting which limited her access to drinking water. Collateral history revealed that she had previously drunk copious amounts of water during the course of any given day and this had served to alleviate the dramatic symptoms of hypernatraemia that were rapidly manifest when her normal intake was curtailed. We outline the fluid management, administration of desmopressin and her subsequent recovery. A literature review of the management of central diabetes insipidus is also covered.

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