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Cytomegalovirus Colitis in a Critically Ill Patient following Elective Repair of an Abdominal Aortic Aneurysm
Author(s) -
Kristján Orri Helgason,
Simon Raby,
Hooman Kamel,
Ian F. Laurenson,
Kate Templeton,
Timothy Walsh
Publication year - 2008
Publication title -
anaesthesia and intensive care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 62
eISSN - 1448-0271
pISSN - 0310-057X
DOI - 10.1177/0310057x0803600119
Subject(s) - medicine , ganciclovir , cytomegalovirus , polymerase chain reaction , colitis , betaherpesvirinae , critically ill , herpesviridae , immunology , human cytomegalovirus , virus , viral disease , gene , chemistry , biochemistry
We describe a case of cytomegalovirus colitis in a critically ill but otherwise immunocompetent 61-year-old male. Infection was demonstrated by histology and confirmed by plasma polymerase chain reaction and detection of cytomegalovirus IgM antibody. The patient was treated with ganciclovir with resolution of the cytomegalovirus viraemia. Cytomegalovirus colitis may be an under-recognised problem in immunocompetent patients who are critically ill. Quantification of plasma cytomegalovirus DNA by polymerase chain reaction is a non-invasive method of supporting the diagnosis and can be used to monitor the treatment of cytomegalovirus infection in the immunocompetent.

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