Open AccessAcute myeloid leukemia with T lymphoblastic lymphoma: a case report and literature review
Author(s) -
Guoquan Yan,
Xianqi Feng,
Shanshan Liu,
Yujie Xu,
Chunxia Mao,
Tianlan Li,
Feng Hou,
Wei Zhang
Publication year - 2021
Publication title -
journal of international medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 57
eISSN - 1473-2300
pISSN - 0300-0605
DOI - 10.1177/03000605211016138
Subject(s) - medicine , lymphoblastic lymphoma , myeloid , lymphoma , immunohistochemistry , myeloid leukemia , bone marrow , cd5 , myeloid sarcoma , lymph node , pathology , myeloperoxidase , immunophenotyping , leukemia , t cell , cancer research , immunology , flow cytometry , immune system , inflammation
Acute myeloid leukemia (AML) with T lymphoblastic lymphoma (T-LBL) is a hematologic tumor of two origins, myeloid and lymphoblastic, and is relatively rare in the same patient. We report a rare case of AML with T-LBL. After the patient was diagnosed, he received standard chemotherapy, which decreased the primitive bone marrow cell percentage from 84% to 5%; however, the enlarged superficial lymph nodes showed no obvious change in size. Immunohistochemistry revealed the following: cluster of differentiation (CD)3 (+), CD5 (+), CD7 (+), transmission disequilibrium test (TDT) (+), myeloperoxidase (MPO) (−), and lysozyme (Lys) (−). The lymph node morphology and immunohistochemical results indicated T-LBL. Therefore, the final diagnosis was AML with T-LBL, with both diseases occurring independently and concurrently.