Open AccessSerum glucose and potassium ratio as a predictive factor for prognosis of acute intracerebral hemorrhage
Author(s) -
Xiaoyu Wu,
Yao-Kun Zhuang,
Yong Cai,
Xiao-Qiao Dong,
Keyi Wang,
Qin Du,
Wenhua Yu
Publication year - 2021
Publication title -
journal of international medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 57
eISSN - 1473-2300
pISSN - 0300-0605
DOI - 10.1177/03000605211009689
Subject(s) - medicine , glasgow coma scale , intracerebral hemorrhage , modified rankin scale , hematoma , receiver operating characteristic , gastroenterology , surgery , ischemic stroke , ischemia
Objective The serum glucose/potassium ratio (GPR) is a potential prognostic predictor for acute brain injury-related diseases. We calculated the serum GPR in patients with acute intracerebral hemorrhage (ICH) and explored its prognostic value for long-term prognoses and ICH severity.Methods This retrospective cohort study consecutively included 92 patients with ICH and 92 healthy controls. The National Institutes of Health Stroke Scale (NIHSS) score, Glasgow coma scale (GCS) score, and hematoma volume were used to assess severity. A modified Rankin Scale score > 2 at 90 days post-stroke was defined as a poor outcome.Results The serum GPR was significantly higher in patients than controls. The serum GPR was weakly correlated with the NIHSS score, GCS score, and hematoma volume. The serum GPR, GCS score, and hematoma volume were independently associated with poor outcomes. In the receiver operating characteristic curve analysis, the serum GPR remarkably discriminated patients at risk of poor outcomes at 90 days. The serum GPR significantly improved the prognostic predictive capability of hematoma volume and tended to increase that of the GCS score.Conclusion Serum GPR is an easily obtained clinical variable for predicting clinical outcomes after ICH.