Open AccessDiagnosis of a granular cell tumour at the abdominal wall using fine needle aspiration cytology and histology: Case report
Author(s) -
Lixia Wang,
Fang Zhu,
Hongqi Shi,
Lou Shanxian,
Wenlong Shen
Publication year - 2015
Publication title -
journal of international medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 57
eISSN - 1473-2300
pISSN - 0300-0605
DOI - 10.1177/0300060515583079
Subject(s) - haematoxylin , pathology , medicine , cytology , histology , eosinophilic , eosin , fine needle aspiration , staining , h&e stain , nucleolus , cytopathology , biopsy , anatomy , nucleus , psychiatry
This case report describes the use of fine needle aspiration cytology to diagnose a granular cell tumour (GCT) that presented as a painless, palpable mass at the abdominal wall in a 50-year-old woman who had had the mass for ≥1 year prior to presentation. Routine haematoxylin and eosin staining of the cytological smears demonstrated that the specimen was predominantly cellular; it contained both cell clusters and single cells with abundant granular cytoplasm and indistinct cell borders. Cells were fragile and had fairly uniform naked nuclei that were scattered with vacuolated and prominent nucleoli. Background material on the smears included eosinophilic, granular cytoplasmic material and some adipose tissue. Neither mitoses nor necrosis were observed. A cytological diagnosis of a GCT was confirmed by histological examination of a surgical specimen stained with haematoxylin and eosin. This case report found that the GCT had a characteristic cytological appearance and that cells with prominent nucleoli can be present in benign GCTs.