Open AccessAssociation between exposure to hepatitis B virus and chronic kidney disease in China
Author(s) -
Qiang Zeng,
Yan Gong,
Sheng-Yong Dong,
Hang Xiang,
Qiang Wu
Publication year - 2014
Publication title -
journal of international medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 57
eISSN - 1473-2300
pISSN - 0300-0605
DOI - 10.1177/0300060514541828
Subject(s) - medicine , disease , kidney disease , virology , hepatitis b virus , china , virus , chronic hepatitis , hepatitis a virus , immunology , political science , law
Objective Hospital-based, cross-sectional study to determine whether exposure to hepatitis B virus (HBV) has an independent effect on the risk of developing chronic kidney disease (CKD).Methods Han Chinese adults undergoing routine physical examinations were recruited. Blood was tested for the presence of hepatitis C virus (HCV) antibodies, HBV surface antigen, and antibodies against HBV core antigen and hepatitis B surface antigen (HBsAg). CKD was defined as estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m 2 or presence of albuminuria.Results The prevalence of HBV exposure was 42.1% (6 418/15 259 participants). There were no significant associations between HBV or HCV status and CKD, low eGFR or albuminuria.Conclusion There was no association between exposure to HBV and the risk of developing CKD in this Chinese study population.