Open AccessTime-dependent association between selective serotonin reuptake inhibitors and hospitalization due to hyponatremia
Author(s) -
Buster Mannheimer,
Henrik Falhammar,
Jan Calissendorff,
Jakob Skov,
Jonatan D. Lindh
Publication year - 2021
Publication title -
journal of psychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.333
H-Index - 114
eISSN - 1461-7285
pISSN - 0269-8811
DOI - 10.1177/02698811211001082
Subject(s) - hyponatremia , medicine , odds ratio , confidence interval , population , depression (economics) , fluvoxamine , reuptake inhibitor , anxiety , pediatrics , anesthesia , psychiatry , serotonin , antidepressant , fluoxetine , receptor , macroeconomics , economics , environmental health
Selective serotonin reuptake inhibitors (SSRIs) have a wide and increasing use for the treatment of depression and anxiety. Previous studies have indicated an increased risk of hyponatremia during the first months of treatment. We aimed to investigate the detailed time-course of SSRI-associated hyponatremia with a high temporal resolution, using registry data encompassing the total Swedish population.
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