Open AccessThe Role of PET/CT for Lung Lesions in Oral Cavity Cancer
Author(s) -
Chang Yuchang,
Hao ShengPo
Publication year - 2012
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1177/0194599812451426a185
Subject(s) - medicine , lung , lung cancer , inflammation , lesion , biopsy , radiology , standardized uptake value , cancer , incidence (geometry) , pathology , positron emission tomography , physics , optics
Objective Determine the significant parameters of PET/CT in the prediction of the nature of lung lesions during the staging of newly diagnosed or recurrent oral cavity cancer. Method We retrospectively reviewed the charts of 183 patients from July 2010 to December 2011 with newly diagnosed or recurrent oral cavity cancer. Twelve cases with positive PET/CT lung lesions (SUVmax >4) subsequently underwent biopsy. The SUVmax, number of lesion, and side were studied. Results A total of 12 patients were collected as suspicious for lung metastases. One case with esophageal cancer was excluded. Five were lung metastases, 3 were second primary lung cancer, and the remaining 3 were chronic inflammation. Comparing with second primary and chronic inflammation, metastases had higher SUVmax but without significant difference ( P value >.05). Metastases and chronic inflammation had higher incidence of multifocal lesions comparing with second primary ( P value, metastases vs second primary:. 008, chronic inflammation vs second primary:. 09). There is no significant difference between the metastases and chronic inflammation ( P value:. 38). For side and lesion, no significance was noted. Conclusion Based on our preliminary data, higher SUVmax value (mean: lung metastases: 6.65, second primary lung cancer: 3.96, chronic inflammation: 3.98) and multifocal lesions favor metastatic lung lesions compared with second primary or chronic inflammation.