Open AccessTopiramate‐Induced Unilateral Ptosis
Author(s) -
Zhao Kathy,
Spiegel Jeffrey H.
Publication year - 2012
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1177/0194599812451426a16
Subject(s) - ptosis , topiramate , discontinuation , medicine , eyelid , anesthesia , surgery , epilepsy , psychiatry
Objective To present the case of a rare ocular side effect induced by topiramate use. Method This is a case of a 43‐year‐old transgender man who presented with unilateral ptosis of the right eye. Ptosis was noted after 4 years of topiramate therapy, prescribed as prophylaxis against migraines. Results While some adverse vision and eye effects associated with the use of topiramate have been documented, eyelid ptosis has only been reported in 0.14% of patients using the drug. Thus, topiramate‐induced ptosis is a very unusual finding. Conclusion Experience with this case has demonstrated that immediate discontinuation of the drug can restore eyelid function within 1 week.