Open AccessEstrogen Receptors in Nasal Mucosa
Author(s) -
Millas Ieda,
Liquidato Bianca M.,
Correa Carla Sant`Anna,
Buck Hudson S.,
Dolci JoseEduardo L.,
Barros Mirna Duarte,
Paes Roberto Antonio Pinto
Publication year - 2011
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1177/0194599811416318a39
Subject(s) - lamina propria , receptor , estrogen , mucous membrane of nose , estrogen receptor , medicine , immunohistochemistry , pill , menstrual cycle , endocrinology , gynecology , hormone , pathology , epithelium , pharmacology , cancer , breast cancer
Objective Evaluate the influence of oral contraceptives on the distribution and concentration of estrogenic receptors in nasal mucosa. Method There were selected 2 groups of 32 women, with regular menstrual cycles, who had undergone nasal surgery. One group of women was taking oral contraceptives and the other was not. Samples of mucosa of inferior nasal turbinate were analyzed by immunohistochemical staining for alpha and beta estrogen receptors. Results A decrease of beta‐receptor in lamina propria cells with the use of oral contraceptives was observed. On the other locations there was not any statistically significant difference. In both groups there was a predominance of beta‐receptor presence. Conclusion Women taking contraceptive pills had a decrease of beta‐receptor in lamina propria cells.