Open AccessA Meta‐analysis of Injection Laryngoplasty vs Thyroplasty
Author(s) -
Shen Tianjie,
Morzaria Sanjay
Publication year - 2011
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1177/0194599811416318a119
Subject(s) - medicine , silicone , laryngoplasty , surgery , treatment modality , web of science , meta analysis , larynx , chemistry , organic chemistry
Objective Compare the long‐term voice outcome following calcium hydroxylapatite injection laryngoplasty (IL) vs silicone medialization laryngoplasty (ML) as the long‐term treatment modalities for the treatment of unilateral vocal fold paralysis (UVFP) through a meta‐analysis study. Method A systematic literature review was performed from MEDLINE, Google Scholar, Web of Science, Scopus, and Cochrane between January 1, 1980, and December 31, 2010. Studies reporting voice outcome after IL with calcium hydroxylappatite and/or ML with silicone for the treatment for UVFP were included. The primary outcome measure was change in Voice Handicap Index (VHI). Results Seven hundred and forty‐two abstracts were screened for relevancy. Seventy‐one articles were reviewed in detail. Twelve studies satisfied the inclusion criteria. The mean VHI score, following IL (n = 209), improved from 68.36 (±6.88) to 32.24 (±7.33). The mean VHI score, following ML (n = 110), improved from 72.22 (±11.06) to 34.02 (±6.48). The improvement in VHI following both techniques was statistically significant. Conclusion Injection laryngoplasty with calcium hydroxylapatite and medialization laryngoplasty with silicone offer comparable voice improvement as long‐term treatment modalities for UVFP. The choice of procedure should be based on planned duration of medialization, patient’s preference, and physician’s preference.