Open AccessTreatment of 183 Sinonasal Tumors: Updating Our Experience
Author(s) -
Guilemany Jose M.,
Montero Cristobal Langdon,
Blanch Josep Lluis,
Alobid Isam
Publication year - 2011
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1177/0194599811415823a169
Subject(s) - medicine , radiation therapy , stage (stratigraphy) , surgery , chemotherapy , cancer , statistical significance , primary tumor , metastasis , paleontology , biology
Objective The current study updated our previous study involving the outcomes and prognostic factors of sinonasal cancer patients treated at our institution. Method A total of 183 sinonasal cancer patients who were treated between 1974 and 2008 with a minimum follow‐up of 2 years were retrospectively reviewed and restaged using the seventh edition of the AJCC staging manual. Results The mean age was 60.89 years (+14.99 years SD), 70.4% males. Tumor stage distribution was: T1:72patients; T2:48p; T3:39p; T4:24p. Ninety‐six patients received surgery as primary treatment, 51 received surgery plus radiotherapy, 7 received surgery plus radiotherapy with/without chemotherapy, and 22 received radiotherapy with/without chemotherapy palliative treatment. The 1‐, 5‐, 10‐year disease free survival rate was 82.3%, 49%, and 34.9%, respectively. There was no significant survival difference between surgery alone and surgery plus radiotherapy. The parameters with statistical prognostic significance were tumor stage, tumor histology, and locoregional failure. Conclusion Although there is a significant advance in survival rates, the failure at the primary site is still the main problem. As a prognostic value of survival, therefore, we should put all our effort to improve the control of the locoregional failure.